Barely Significant
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Bortezomib-induced aerobic glycolysis contributes to chemotherapy-induced painful peripheral neuropathy.

Mol Pain · 2019 · PMC6452581 · PMID 30810076

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highly significantno p-value reported
Crucially, the data reveal that targeted inhibition of the enzymes that maintain aerobic glycolysis can serve as a valid strategy for treating CIPN—a highly significant clinical challenge.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.