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Levels of trace elements and potential toxic elements in bovine livers: A trend analysis from 2007 to 2018.

PLoS One · 2019 · PMC6456170 · PMID 30964882

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an increasing trendno p-value reported
There was an increasing trend in poisoning from these metals during the study period.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.