There was a highly significant overlap between the DEGs in the nucleus accumbens identified by our study and an independent study that characterized gene expression in the ventral striatum (a region containing the nucleus accumbens) from ethanol-naïve male HDID-1 and HS/Npt mice [ 10 ] (hypergeometric p < 5E-28), providing validation for our gene expression platform.
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Dissecting Brain Networks Underlying Alcohol Binge Drinking Using a Systems Genomics Approach.
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