Accordingly, in our cohort, cRAGE inversely correlates with the inflammatory marker PAI-1 ( Table 2 ), known to increase in age-associated clinical conditions including cardiovascular diseases, type 2 diabetes (T2DM), obesity and inflammation [ 50 ] and shows also an almost significant inverse correlation with CRP ( Table 2 ).
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Modulation of soluble receptor for advanced glycation end-products (RAGE) isoforms and their ligands in healthy aging.
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