Feedforward inhibition ahead of ictal wavefronts is provided by both parvalbumin- and somatostatin-expressing interneurons.

There was a highly significant difference in the level of participation between those neurons that were active in the pre‐ictal period vs . those that were recruited only in the later stages of the ictal event (‘pre’, median = 37% participation; ‘late’, median = 0% participation; Wilcoxon rank sum test, P = 5.6 × 10 −8 ).

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