Smoking Dependent Alterations in Bone Formation and Inflammation Represent Major Risk Factors for Complications Following Total Joint Arthroplasty.

J Clin Med · 2019 · PMC6462941 · PMID 30909629

Europe PMC DOI

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0.0010

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highly significantp < 0.001actually significant

Interestingly, while in patients receiving primary TJA, the frequency of malaise (nausea and/or vomitus) prior surgery only trends to be higher in the group that developed complications (17.7%) when compared with the group that did not develop adverse events (9.3%; OR = 2.220; p = 0.097), this effect was highly significant in patients receiving revision TJA (8.6% vs. 31.3%; OR = 4.543; p < 0.001).

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