Early life stress disrupts intestinal homeostasis via NGF-TrkA signaling.

Nat Commun · 2019 · PMC6465335 · PMID 30988299

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highly significantno p-value reported

Moreover, there is a highly significant correlation between NGF and serotonin in human and they are markedly upregulated in IBS-D patients.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.