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miRNA-766 induces apoptosis of human colon cancer cells through the p53/Bax signaling pathway by MDM4.

Exp Ther Med · 2019 · PMC6468453 · PMID 31007746

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an increasing trendno p-value reported
The morbidity rate of colon cancer in China has exhibited an increasing trend in recent years.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.