Moderate Exercise Improves Experimental Cancer Cachexia by Modulating the Redox Homeostasis.

Body weight loss in the C26 hosts ( Figure 1 A) was slightly, but with borderline significance ( p = 0.051), attenuated by exercise ( Figure 1 A,B), while no differences could be observed between sedentary and exercised controls ( Figure 1 A).

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Although the differences were not significant, exercised healthy mice showed an increasing trend in both Nrf2 and Keap1 levels ( Figure 4 A), resulting in a Nrf2/Keap1 ratio comparable to control values ( Figure 4 B).

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