The Suv420h histone methyltransferases regulate PPAR-γ and energy expenditure in response to environmental stimuli.

Sci Adv · 2019 · PMC6469946 · PMID 31001581

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highly significantP = 3.1 × 10 −8actually significant

For the RNA-seq Diet, we again found a highly significant overlap with 52% of up-regulated genes in Suv420h dKO overlapping with PPAR-γ targets (odds ratio, 1.6; 95% CI, 1.37 to 1.93; Fisher P = 3.1 × 10 −8 ).

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