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Pharmacologic adjunctive to insulin therapies in type 1 diabetes: The journey has just begun.

World J Diabetes · 2019 · PMC6475707 · PMID 31040899

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an increasing trendno p-value reported
Furthermore, metformin use has been linked to an increasing trend of the incidence of hypoglycemia[ 19 ], a clue that requires further assessment by additional studies, particularly with the use of Continuous Glucose Monitoring systems.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.