Barely Significant
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Global Brain Transcriptome Analysis of a Tpp1 Neuronal Ceroid Lipofuscinoses Mouse Model.

ASN Neuro · 2019 · PMC6475859 · PMID 31003587

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highly significantp < 8.5E-36actually significant
IPA analysis also identifies, in both brain areas, several highly significant upstream regulators; that is, the transcription factors, Irf3 (F/M: p < 8.5E-36, z = 5.2; Cb: p < 6.6E-17, z = 4.7); Irf7 (F/M: p < 1.1E-28, z = 4.6; Cb: p < 5.7E-15, z = 4.1); the interleukin Ifng (interferon gamma; F/M: p < 9.9E-33, z = 6.3; Cb: p < 1.5E-26, z = 7.1); and interferon alpha/beta receptors ( Ifnar1 and Ifnar2 ; F/M: p < 1.4E-44, z = 6.2; Cb: p < 1.5E-25, z = 6.2).

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