Genetic identification of brain cell types underlying schizophrenia.

In both human studies, oligodendrocyte precursor cells (OPCs) were significant or close to significance but it is hard to judge if this is related to a loss of neuronal-specific signal in snRNAseq (note that OPCs showed stronger signal in OPCs in mouse snRNAseq vs scRNAseq; Figure 2 and Supplementary Figure 10d ).

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These gene sets are highly significant, replicate well, and are often implicated in both common and rare variant studies.

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