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Trends in the use of antibiotics among Korean children.

Korean J Pediatr · 2019 · PMC6477546 · PMID 30852884

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an increasing trendno p-value reported
Children aged younger than 6 years had the highest level of use (59.21 DID) in 2014, and showed an increasing trend each year, consistent with previous findings.

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a decreasing trendno p-value reported
However, there was a decreasing trend in the prevalence of polypharmacy, from 65.3% in 2002 to 46.6% in 2013, which likely reflects the policy-driven change since the early 2000s that stemmed from quality assessment and a drug utilization review by the HIRA service [ 7 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.