Barely Significant
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Akebia Saponin D Regulates the Metabolome and Intestinal Microbiota in High Fat Diet-Induced Hyperlipidemic Rats.

Molecules · 2019 · PMC6479315 · PMID 30939835

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markedly significantno p-value reported
Secondly, the ASD-treated group showed a markedly significant increased in the relative abundance of norank_f_Bacteroidales_S24-7_group, Lachnospiraceae_NK4A136_group and Ruminococcus_1 which are short-chain fatty acid (SCFA)-producing bacteria [ 47 , 48 , 49 ], that not only provide energy for the intestinal mucosa cells and promote the metabolism and growth of cells in the colon but also lower the environmental pH of the colon, reduce the growth of harmful bacteria and prevent intestinal dysfunction.

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