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<i>Helicobacter pylori</i> eradication: the relevance of a periodic update.

Ann Gastroenterol · 2019 · PMC6479652 · PMID 31040635

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an increasing trendno p-value reported
Hence, in our area there is an increasing trend to repeat the same treatment after a first failure, despite a long background in the management of H. pylori infection [ 4 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.