While SMAD3 was not significantly differentially phosphorylated under conditions of low pO 2, as compared to normoxia, pSmad1/5/8 levels showed a decreasing trend with decreasing pO 2 .
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Bioreactor-Controlled Physoxia Regulates TGF-β Signaling to Alter Extracellular Matrix Synthesis by Human Chondrocytes.
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