Low-Field, Benchtop NMR Spectroscopy as a Potential Tool for Point-of-Care Diagnostics of Metabolic Conditions: Validation, Protocols and Computational Models.

Again, very highly significant linear correlations were found between the TSP-normalised α-anomeric-C1-H glucose proton resonance intensity and total glucose standard concentration ( Section 6 , R 2 = 0.989). 5. 60 MHz 1 H NMR Benchtop Spectrometer Protocol: Biofluid Analysis Recommendations 5.1.

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inary glucose concentration and μ that concentration in the absence of these sources of variation. y ijk = μ + M i + P j + e ijk (1) This analysis found that there were very highly significant differences between participants ( p < 10 −4 ), as expected; however, that between methods/techniques was barely statistically significant, and the only difference found between these four form of analyses using further analysis by Tukey’s highest significant difference (HSD) test, was that between 400 MHz 1 H NMR-determined glucose levels and those obtained from the above dipstick approach, the latter being significantly greater than the former ( p = 0.033).

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