High frequency of association of rheumatic/autoimmune diseases and untreated male hypogonadism with severe testicular dysfunction.

Serum testosterone and estradiol 17β levels were lower in those with RAD, but only the difference in testosterone was highly significant (1.0 ± 0.7 vs 2.7 ± 1.2 ng/ml, P = 0.0005) (see Supplementary Table 1 ).

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