Transcriptome analysis of normal-appearing white matter reveals cortisol- and disease-associated gene expression profiles in multiple sclerosis.

Acta Neuropathol Commun · 2019 · PMC6485096 · PMID 31023360

Europe PMC DOI

hedged sentence

0.0950

closest p · 1.9× alpha

0.0950

boldest claim

The sentences

a trend towards significancep = 0.095so close (0.05 < p ≤ 0.1)

In addition, cortisol levels in CSF correlated with duration of MS (r = 0.490, p = 0.039) and with a trend towards significance with time to a score of 6 on the expanded disability status scale (EDSS6) (r = 0.432, p = 0.095), confirming earlier findings that high HPA-axis activity coincides with slower disease progression and relatively mild MS [ 35 , 58 ].

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