Furthermore, these highly significant decreases applied both to Vγ6 + IL-17A-producing thymocytes, that develop primarily in the fetus, display very limited TCR diversity, and that principally populate the uterine and tongue epithelia 16 - 18 , and to Vγ4 + IL-17A-producing thymocytes that are more diverse than Vγ6 + cells, and that primarily populate the peritoneum, spleen, LNs, dermis and intestinal lamina propria 5 , 10 ( Fig. 2c ).
← all excerpts
Innate-like T cells straddle innate and adaptive immunity by altering antigen-receptor responsiveness.
1
—
—