USP10 modulates the SKP2/Bcr-Abl axis via stabilizing SKP2 in chronic myeloid leukemia.

Cell Discov · 2019 · PMC6488640 · PMID 31044085

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highly significantno p-value reported

A highly significant implication of our discovery of the USP10-SKP2-Bcr-Abl pathway is its provision of a new strategy to overcome the resistance to TKIs caused by T315I mutation.

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