Inferring cancer dependencies on metabolic genes from large-scale genetic screens.

However, the correlation between metabolic gene dependency scores and media type remained highly significant when controlling for the cell culture type; for ~ 90% of the metabolic genes whose RNAi- or CRISPR-based dependency score correlate with media type, the correlation remains significant when controlling for cell culture type (FDR-corrected Spearman partial correlation p value < 0.05).

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