IL-11 is essential in promoting osteolysis in breast cancer bone metastasis via RANKL-independent activation of osteoclastogenesis.

Cell Death Dis · 2019 · PMC6491651 · PMID 31040267

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highly significantno p-value reported

A recent cohort study of 89 patients revealed a statistically highly significant association between IL-11 expression in primary tumors and an increased risk for development of bone metastasis 35 .

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