Epigenetic regulation of gene expression in Chinese Hamster Ovary cells in response to the changing environment of a batch culture.

Although the trend of active transcription mark (H3K36me3) shows a highly significant ( p < 0.01) correlation (Supporting Information Figure 7b) with expression levels, the trends for promoter marks (H3K4me3 and H3K27ac) behave noisy (Figure 3 b; Supporting Information Figure 7b). 3.3.1.

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