cIAP1/2 inhibition synergizes with TNF inhibition in autoimmunity by down-regulating IL-17A and inducing T<sub>regs</sub>.

Sci Adv · 2019 · PMC6494502 · PMID 31049403

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highly significantno p-value reported

However, it is important to emphasize that, despite increased TNF-α levels in serum, we observed a highly significant reduction in arthritis severity associated with increased levels of IL-10 and T regs .

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