Effects of targeted memory reactivation during sleep at home depend on sleep disturbances and habituation.

In a 2 × 3 ANOVA, we observed a highly significant interaction between the within-subject factor “cueing” and sleep disturbance group ( F (2,63) = 5.58, P = 0.006, η 2 = 0.15): Over the three nights of stimulation, undisturbed sleepers showed a significant memory improvement by TMR by ca. 12% points similar to previous findings in the sleep lab (cued words: 167.63 ± 1.15% vs. uncued: 155.41 ± 4.41%; t (14) = 3.25, P = 0.006, see Fig. 2 a).

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