of borderline significanceP =0.0919
22 , 23 , 31 , 32 , 35 The retrospective cohort conducted by Burgio et al 31 reported that in the multivariate analysis, high CHGA expression was a predictor of PFS (HR=2.70, 95% CI: 1.30–5.20; P =0.0047), while CHGA levels remained of borderline significance of OS (HR=1.90, 95% CI: 0.90–4.10; P =0.0919).