This study suggests that the variant of ATM D1853N polymorphism is linked with the more risk of developing a HNPCC-related cancer which remains to be highly significant ( 10 ) evidence of link between a single non-conservative point mutation in ATM and expression of phenotype in HNPCC ( 32 ) ( Fig. 4 ).
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A review on role of ATM gene in hereditary transfer of colorectal cancer.
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