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Metal nickel exposure increase the risk of congenital heart defects occurrence in offspring: A case-control study in China.

Medicine (Baltimore) · 2019 · PMC6504320 · PMID 31045777

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an increasing trendno p-value reported
First, the previous study showed that cadmium and nickel present a synergistic effect and with the increase of the concentration proportion of cadmium, the area of synergistic effect had an increasing trend.

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