Efficient reduction of synthetic mRNA induced immune activation by simultaneous delivery of B18R encoding mRNA.

J Biol Eng · 2019 · PMC6509845 · PMID 31168319

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highly significantno p-value reported

IFNβ stimulation of cells transfected with B18R mRNA or incubated with B18R protein resulted in a highly significant reduction of Mx1 expression, which showed the successful inhibition of IFNβ by the produced B18R protein in the cells (Fig. 3 ).

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