Acute transient cognitive dysfunction and acute brain injury induced by systemic inflammation occur by dissociable IL-1-dependent mechanisms.

Mol Psychiatry · 2019 · PMC6510649 · PMID 29875474

Europe PMC DOI

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highly significantp < 0.001actually significant

There was a significant effect of treatment ( F 2,234 = 4.78, p = 0.139) and an interaction of treatment and time ( F 12,234 = 3.67, p < 0.0001) and Bonferroni post hoc comparison showed a highly significant difference between ME7 + LPS + IL-1RA and ME7 + LPS + veh at 5 h ( p < 0.001).

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