Overlooked roles of DNA damage and maternal age in generating human germline mutations.

Proc Natl Acad Sci U S A · 2019 · PMC6511033 · PMID 31019089

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marginally significantP = 0.035actually significant

Intriguingly, Poisson regression of the count of paternal mutations on both parental ages revealed a marginally significant effect of maternal age ( P = 0.035) and a slight but nonsignificant improvement in the fit compared with a model with paternal age only (∆AIC = −2.4; SI Appendix , Table S8 ).

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