PLZF limits enhancer activity during hematopoietic progenitor aging.

Nucleic Acids Res · 2019 · PMC6511862 · PMID 30892634

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We observed that PLZF overexpression induced H3K27ac changes in active promoters and active enhancers with a highly significant decrease at active enhancers (Figure 2A , Supplemental Figure S2B), suggesting that PLZF would modify active enhancer activity in 416b cells.

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