Modulation of anterior cingulate cortex reward and penalty signalling in medication-naive young-adult subjects with depressive symptoms following acute dose lurasidone.

Figure 3 illustrates the finding that the absolute difference in neural activity between lurasidone and placebo increased as a function of depression scores. A similar pattern of results, namely a signal normalisation, was found in the OFC ( F = 4.94, df = 1, 37, p = 0.032), but the interaction fell short of significance after Bonferroni adjustment (see the online Supplementary Results).

also in 361 other papers