Glutamine to proline conversion is associated with response to glutaminase inhibition in breast cancer.

Positive signals with stars (*) indicate that there is a significantly higher amount of the metabolite in 13 C-enriched samples compared to natural abundance samples, whereas up arrowheads (^) indicate borderline significance. b) Amount of 13 C-labeled metabolites in the tumors, calculated by subtracting natural abundance spectra from 13 C-enriched spectra.

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We observed that MAS98.12 xenografts display a borderline significant higher expression of MYC than MAS98.06 xenografts.

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