Impact of delisting high-strength opioid formulations from a public drug benefit formulary on opioid utilization in Ontario, Canada.

Pharmacoepidemiol Drug Saf · 2019 · PMC6518867 · PMID 30873707

Europe PMC DOI

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an increasing trendno p-value reported

Following the policy, the weekly median daily dose of publicly funded opioids began to decrease (compared with an increasing trend prepolicy), reflecting a slope change of −3.9 MME per week (95% CL, −5.5 to −2.3).

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