Barely Significant
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Effects of opioid receptor stimulation and blockade on touch pleasantness: a double-blind randomised trial.

Soc Cogn Affect Neurosci · 2019 · PMC6523440 · PMID 30951167

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marginally significantno p-value reported
Pharmacological MOR blockade led to ~10% marginally significant increases in average ratings of pleasantness for both fast and slow brushing compared to baseline, consistent with earlier findings in primates but not in rodents.

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