This is evidenced by a strong and highly significant inverse correlation of the ratio of log-transformed p- values from these two tests, log 10 ( p meta )/log 10 ( p Fisher ), with the heterogeneity coefficient I 2 ( Table 2 ; r Pearson = −0.874, p = 2.0 × 10 −21 ).
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Pleiotropic Meta-Analysis of Age-Related Phenotypes Addressing Evolutionary Uncertainty in Their Molecular Mechanisms.
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