A bi-directional genetic study revealed that though the effect of lower 25D on BMI may not be significant but higher BMI leads to lower 25D ( 88 ) various explanations have been proposed to define this association, such as reduced cutaneous synthesis ( 89 ) and altered metabolism ( 90 ).
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Vitamin D Deficiency in the Gulf Cooperation Council: Exploring the Triad of Genetic Predisposition, the Gut Microbiome and the Immune System.
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