Role of T lymphocytes and papain enzymatic activity in the protection induced by the cysteine protease against <i>Schistosoma mansoni</i> in mice.

Highly significant ( P < 0.005) reductions in worm burden required competent T lymphocytes, while significant increases ( P < 0.05) of >80% in dead parasite ova in the small intestine were independent of T cell activity and likely relied on the innate immune axis.

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