24 As protein-protein interactions have been shown to mediate exosome attachment and uptake into cells, the presence of proteins such as CD47 and CD267 in the membrane proteome of HPV(+) exosomes and their absence/paucity in HPV(-) exosomes is highly significant.
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Proteomes of exosomes from HPV(+) or HPV(-) head and neck cancer cells: differential enrichment in immunoregulatory proteins.
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