highly significantp < 0.01
At 24 h, both concentrations of CuO NMs and CuSO 4 caused a highly significant decrease in TEER in the Caco-2/Raji B co-culture (p < 0.01) and the Caco-2/HT29-MTX model [6.34 Cu μg/cm 2 and 12.68 Cu μg/cm 2 (p < 0.05)].
At 24 h, both concentrations of CuO NMs and CuSO 4 caused a highly significant decrease in TEER in the Caco-2/Raji B co-culture (p < 0.01) and the Caco-2/HT29-MTX model [6.34 Cu μg/cm 2 and 12.68 Cu μg/cm 2 (p < 0.05)].