Mitochondria function associated genes contribute to Parkinson's Disease risk and later age at onset.

NPJ Parkinsons Dis · 2019 · PMC6531455 · PMID 31123700

Europe PMC DOI

hedged sentences

0.0000

closest p · 0.0× alpha

0.0000

boldest claim

The sentences

highly significantp -value = 3.56E-05actually significant

Nonetheless, the highly significant p -value we obtain for the association mitochondrial genes and AAO of PD ( p -value = 3.56E-05) and the recognized importance of mitochondrial function in aging would suggest that this finding is likely to be robust.

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an overall trendno p-value reported

This analysis was performed using PRS since it has been consistently found to be the main genetic predictor of AAO 6 , 26 – 28 with higher genetic risk scores being significantly associated with an overall trend for earlier AAO of disease.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.