Celiac Disease in Children, Particularly with Accompanying Type 1 Diabetes, Is Characterized by Substantial Changes in the Blood Cytokine Balance, Which May Reflect Inflammatory Processes in the Small Intestinal Mucosa.

The levels of eight cytokines showed a highly significant correlation with the degree of small bowel mucosa damage according to the Marsh classification: IL-27 ( r = 0.46; P < 0.0001), sIL-2Ra ( r = 0.41; P = 0.0005), IL-15 ( r = 0.40; P = 0.0005), IL-8 ( r = 0.40; P = 0.0004), IL-5 ( r = 0.30; P = 0.01), IP-10 (IFN γ inducible protein 10 or CXCL10) ( r = 0.27; P = 0.02), sTNFRII ( r = 0.26; P = 0.03), and MIP-1 β ( r = 0.25; P = 0.03).

also in 132,142 other papers