Optimizing locked nucleic acid/2'-O-methyl-RNA fluorescence in situ hybridization (LNA/2'OMe-FISH) procedure for bacterial detection.

Using those designs, most of the quadratic models obtained for each bacterium were highly significant, as is evident from high Model F-values and low p -values ( p <0.05) ( S4 Table ), confirming the adequacy of the model fits.

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