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Dimethyl fumarate dosing in humans increases frataxin expression: A potential therapy for Friedreich's Ataxia.

PLoS One · 2019 · PMC6546270 · PMID 31158268

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an overall trendno p-value reported
DMF treated patient cells showed an overall trend of decrease in R-loop enrichment compared to untreated patient cells with significant decrease at UTR-Ex1 and UP GAA loci by 3.6 and 3.4 fold respectively.

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