The Inflammatory Response After Ischemic Stroke: Targeting β₂ and β₁ Integrins.

The early recruitment and infiltration of neutrophils across the BBB appears to be highly significant in stroke, as high neutrophilic infiltration is associated with damaged cerebrovasculature ( Enzmann et al., 2013 ), while depletion reduces infarct volume and dysfunction in stroke models ( Chou et al., 2004 ).

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