Splice-Break: exploiting an RNA-seq splice junction algorithm to discover mitochondrial DNA deletion breakpoints and analyses of psychiatric disorders.

Nucleic Acids Res · 2019 · PMC6547454 · PMID 30869147

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highly significantP = 2.98e −50actually significant

This result was also reflected in our highly significant Pearson's correlation analysis of the cumulative deletion read % between Splice-Break and MitoDel (Pearson's r : 0.950; P = 2.98e −50 ) ( Supplemental Figure S14J ).

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