Testosterone Deficiency Caused by Castration Modulates Mitochondrial Biogenesis Through the AR/PGC1α/TFAM Pathway.

Front Genet · 2019 · PMC6548818 · PMID 31191617

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The mtDNA copy numbers in some endocrine glands were also lower in the castration group than the control, with a significant decrease in seminal vesicle (fold-change = 0.54; P < 0.05) and a decreasing trend in prostate and mammary gland.

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